Sensitive Nonradiometric Method for Determining Thymidine Kinase 1 Activity
نویسندگان
چکیده
منابع مشابه
Sensitive nonradiometric method for determining thymidine kinase 1 activity.
BACKGROUND Thymidine kinase 1 (TK1) is a cytoplasmic enzyme, produced only in the S-phase of proliferating cells, that has potential as a tumor marker. Specific determination of TK1 in serum is difficult, in part because of differences in the physical properties of serum TK1 compared with cytoplasmic TK1. METHODS The first step in the new assay was phosphorylation of 3'-azido-2',3'-deoxythymi...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2004
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2003.030379